Hormone receptors in the endocrine system often trigger changes in gene expression to alter the activities of key biochemical or physiological pathways. These hormones are released by cells in one part of the body, enter the circulatory system to distribute throughout the body and bind specific receptors in other cells. Information in the endocrine system is transmitted through several small molecules, peptides and proteins that function as hormones.
Along with the nervous system, the endocrine system coordinates the activities of cells in different organs and tissues to control physiological parameters or generate system-wide responses to environmental changes.
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